靶标:
USP46
产品别名:
USP46; ubiquitin specific peptidase 46; ubiquitin specific peptidase 46; ubiquitin carboxyl-terminal hydrolase 46; deubiquitinating enzyme 46; ubiquitin thioesterase 46; ubiquitin thiolesterase 46; ubiquitin-specific-processing protease 46;
背景信息:
Modification of cellular proteins by ubiquitin is an essential regulatory mechanism controlled by the coordinated action of multiple ubiquitin-conjugating and deubiquitinating enzymes. USP46 belongs to a large family of cysteine proteases that function as deubiquitinating enzymes (Quesada et al., 2004 [PubMed 14715245]).[supplied by OMIM, Jun 2009],