靶标:
Polr1e
产品别名:
53kDa; AU042259; D030019D19Rik; Paf53; Praf1; Polr1e; polymerase (RNA) I polypeptide E; polymerase (RNA) I polypeptide E; DNA-directed RNA polymerase I subunit RPA49; DNA-directed RNA polymerase I subunit E; RNA polymerase I associated factor (Paf53); RNA polymerase I subunit A49; RNA polymerase I-associated factor 53; polymerase (RNA) I associated factor 1;
背景信息:
function:DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors. Appears to be involved in the formation of the initiation complex at the promoter by mediating the interaction between Pol I and UBTF/UBF.,similarity:Belongs to the eukaryotic RPA49/POLR1E RNA polymerase subunit family.,subunit:Component of the RNA polymerase I (Pol I) complex consisting of at least 13 subunits (By similarity). Interacts with PAF49/CD3EAP. Also binds UBTF/UBF.,