靶标:
JAM2
产品别名:
C21orf43; CD322; IBGC8; JAM-B; JAMB; PRO245; VE-JAM; VEJAM; JAM2; junctional adhesion molecule 2; junctional adhesion molecule 2; junctional adhesion molecule B; JAM-2; JAM-IT/VE-JAM; vascular endothelial junction-associated molecule; 连接粘附分子2; 连接附着分子2(JAM2);
背景信息:
This gene belongs to the immunoglobulin superfamily, and the junctional adhesion molecule (JAM) family. The protein encoded by this gene is a type I membrane protein that is localized at the tight junctions of both epithelial and endothelial cells. It acts as an adhesive ligand for interacting with a variety of immune cell types, and may play a role in lymphocyte homing to secondary lymphoid organs. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2012],