靶标：
Crlf2
产品别名：
CRLM2； Ly114； Tpte2； Tslpr； Crlf2； cytokine receptor-like factor 2； cytokine receptor-like factor 2； cytokine receptor-like factor 2； TSLP receptor； cytokine receptor-like molecule 2； lymphocyte antigen 114； thymic stromal lymphopoietin protein receptor； thymic stromal-derived lymphopoietin, receptor； transmembrane phosphoinositide 3-phosphatase and tensin homolog 2； type I cytokine receptor delta 1； 胸腺基质淋巴细胞生成素-1； 胸腺基质淋巴细胞生成素受体；
背景信息：
This gene encodes a member of the type I cytokine receptor family. The encoded protein is a receptor for thymic stromal lymphopoietin (TSLP). Together with the interleukin 7 receptor (IL7R), the encoded protein and TSLP activate STAT3, STAT5, and JAK2 pathways, which control processes such as cell proliferation and development of the hematopoietic system. Rearrangement of this gene with immunoglobulin heavy chain gene (IGH) on chromosome 14, or with P2Y purinoceptor 8 gene (P2RY8) on the same X or Y chromosomes is associated with B-progenitor acute lymphoblastic leukemia (ALL) and Down syndrome ALL. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2014],
