靶标:
DPP10
产品别名:
DPL2; DPPY; DPRP-3; DPRP3; DPP10; dipeptidyl peptidase like 10; dipeptidyl peptidase like 10; inactive dipeptidyl peptidase 10; DPP X; dipeptidyl peptidase 10; dipeptidyl peptidase IV-related protein 3; dipeptidyl peptidase X; dipeptidyl peptidase-like protein 2; dipeptidyl-peptidase 10 (inactive); dipeptidyl-peptidase 10 (non-functional); 二肽基肽酶10; 二肽基肽酶10(DPP10);
背景信息:
This gene encodes a single-pass type II membrane protein that is a member of the S9B family in clan SC of the serine proteases. This protein has no detectable protease activity, most likely due to the absence of the conserved serine residue normally present in the catalytic domain of serine proteases. However, it does bind specific voltage-gated potassium channels and alters their expression and biophysical properties. Mutations in this gene have been associated with asthma. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008],