靶标:
TRIM54
产品别名:
MURF; MURF-3; RNF30; muRF3; TRIM54; tripartite motif containing 54; tripartite motif containing 54; tripartite motif-containing protein 54; muscle-specific RING finger protein 3; ring finger protein 30; 肌肉特定环指蛋白3; 肌肉特异性环指蛋白3;
背景信息:
The protein encoded by this gene contains a RING finger motif and is highly similar to the ring finger proteins RNF28/MURF1 and RNF29/MURF2. In vitro studies demonstrated that this protein, RNF28, and RNF29 form heterodimers, which may be important for the regulation of titin kinase and microtubule-dependent signal pathways in striated muscles. Alternatively spliced transcript variants encoding distinct isoforms have been reported.