靶标:
TMPRSS4
产品别名:
CAP2; CAPH2; MT-SP2; TMPRSS3; TMPRSS4; transmembrane serine protease 4; transmembrane serine protease 4; transmembrane protease serine 4; channel-activating protease 2; channel-activating serine protease 2; membrane-type serine protease 2; transmembrane protease, serine 4; transmembrane serine protease 3; type II membrane serine protease; 膜型丝氨酸蛋白酶2; 跨膜丝氨酸蛋白酶4(TMPRSS4);
背景信息:
This gene encodes a member of the serine protease family. Serine proteases are known to be involved in a variety of biological processes, whose malfunction often leads to human diseases and disorders. This gene was identified as a gene overexpressed in pancreatic carcinoma. The encoded protein is membrane bound with a N-terminal anchor sequence and a glycosylated extracellular region containing the serine protease domain. Multiple transcript variants encoding different isoforms have been found for this gene.