靶标:
Gorasp1
产品别名:
GRASP65; Gorasp1; golgi reassembly stacking protein 1; golgi reassembly stacking protein 1; Golgi reassembly-stacking protein 1; golgi peripheral membrane protein p65; golgi reassembly-stacking protein of 65 kDa; 高尔基体外周膜蛋白p65;
背景信息:
The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. The protein encoded by this gene is a membrane protein involved in establishing the stacked structure of the Golgi apparatus. It is a caspase-3 substrate, and cleavage of this encoded protein contributes to Golgi fragmentation in apoptosis. This encoded protein can form a complex with the Golgi matrix protein GOLGA2, and this complex binds to the vesicle docking protein p115. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013],