靶标：
SULF2
产品别名：
HSULF-2； SULF2； sulfatase 2； sulfatase 2； extracellular sulfatase Sulf-2； 硫酸酯酶2(SULF2)； 硫酸酯酶2蛋白；
背景信息：
Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endosulfatases, such as SULF2, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules (Dai et al., 2005 [PubMed 16192265]).
