靶标：
CENPJ
产品别名：
BM032； CENP-J； CPAP； LAP； LIP1； MCPH6； SASS4； SCKL4； Sas-4； CENPJ； centromere protein J； centromere protein J； centromere protein J； LAG-3-associated protein； LYST-interacting protein 1； LYST-interacting protein LIP1； LYST-interacting protein LIP7； Spindle assembly abnormal 4； centrosomal P4.1-associated protein； 着丝粒蛋白J； 着丝粒蛋白J(CENPJ)；
背景信息：
This gene encodes a protein that belongs to the centromere protein family. During cell division, this protein plays a structural role in the maintenance of centrosome integrity and normal spindle morphology, and it is involved in microtubule disassembly at the centrosome. This protein can function as a transcriptional coactivator in the Stat5 signaling pathway, and also as a coactivator of NF-kappaB-mediated transcription, likely via its interaction with the coactivator p300/CREB-binding protein. Mutations in this gene are associated with primary autosomal recessive microcephaly, a disorder characterized by severely reduced brain size and mental retardation. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Apr 2012],
