靶标:
RPRD1A
产品别名:
HsT3101; P15RS; RPRD1A; regulation of nuclear pre-mRNA domain containing 1A; regulation of nuclear pre-mRNA domain containing 1A; regulation of nuclear pre-mRNA domain-containing protein 1A; CDKN2B-related protein; Cyclin-dependent kinase inhibitor 2B-related protein (p15INK4B-related protein); cyclin-dependent kinase 2B-inhibitor-related protein; p15INK4B-related protein; 细胞周期依赖性激酶抑制相关蛋白;
背景信息:
This gene encodes a cell-cycle and transcription regulatory protein. The encoded protein interacts with the cell cycle inhibitor cyclin-dependent kinase 4 inhibitor B and may function as a negative regulator of G(1)/S phase progression. This protein also forms homo- and hetrodimers with the protein, regulation of nuclear pre-mRNA domain-containing protein 1B, to form a scaffold that interacts with the C-terminal domain of RNA polymerase II subunit B1 and regulates several aspects of transcription. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 16.