靶标：
THAP1
产品别名：
DYT6； THAP1； THAP domain containing 1； THAP domain containing 1； THAP domain-containing protein 1； 4833431A01Rik； THAP domain containing, apoptosis associated protein 1； THAP domain protein 1； nuclear proapoptotic factor； 核凋亡因子THAP1；
背景信息：
The protein encoded by this gene contains a THAP domain, a conserved DNA-binding domain. This protein colocalizes with the apoptosis response protein PAWR/PAR-4 in promyelocytic leukemia (PML) nuclear bodies, and functions as a proapoptotic factor that links PAWR to PML nuclear bodies. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
