靶标：
ZWILCH
产品别名：
KNTC1AP； hZwilch； ZWILCH； zwilch kinetochore protein； zwilch kinetochore protein； protein zwilch homolog； Zwilch, kinetochore associated, homolog； homolog of Drosophila Zwilch； 着丝粒ZWILCH蛋白；
背景信息：
This protein is essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. And it is required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. ZWILCH gene is deleted in a patient suffering from colorectal cancer with chromosomal instability.
