靶标:
PPP2R3C
产品别名:
C14orf10; G4-1; G5pr; GDRM; SPGF36; PPP2R3C; protein phosphatase 2 regulatory subunit B''gamma; protein phosphatase 2 regulatory subunit B''gamma; serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma; protein phosphatase 2 (formerly 2A), regulatory subunit B''; protein phosphatase 2, regulatory subunit B'', gamma; protein phosphatase subunit G5PR; rhabdomyosarcoma antigen MU-RMS-40.6A; rhabdomyosarcoma antigen Mu-RMS-40.6C;
背景信息:
This gene encodes a regulatory subunit of the serine/threonine phosphatase, protein phosphatase 2. This protein is localized to both nuclear and cytoplasmic regions depending on cell cycle phase. Homozygous conditional knockout mice for this gene exhibit reduced numbers and impaired proliferation of immune system B cells. This protein may regulate the expression of the P-glycoprotein ATP-binding cassette transporter through its phosphatase activity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015],