靶标:
TRPM7
产品别名:
ALSPDC; CHAK; CHAK1; LTRPC7; LTrpC-7; TRP-PLIK; TRPM7; transient receptor potential cation channel subfamily M member 7; transient receptor potential cation channel subfamily M member 7; transient receptor potential cation channel subfamily M member 7; LTRPC ion channel family member 7; channel-kinase 1; long transient receptor potential channel 7; transient receptor potential-phospholipase C-interacting kinase; 瞬时受体电位离子通道蛋白7(M亚家族); 转化受体电位阳离子通道亚家族M成员7(TRPM7);
背景信息:
transient receptor potential cation channel subfamily M member 7(TRPM7) Homo sapiens The protein encoded by this gene is both an ion channel and a serine/threonine protein kinase. The kinase activity is essential for the ion channel function, which serves to increase intracellular calcium levels and to help regulate magnesium ion homeostasis. Defects in this gene are a cause of amyotrophic lateral sclerosis-parkinsonism/dementia complex of Guam. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2014],