靶标：
Asah2
产品别名：
AI585898； Asah2； N-acylsphingosine amidohydrolase 2； N-acylsphingosine amidohydrolase 2； neutral ceramidase； N-CDase； NCDase； acylsphingosine deacylase 2； neutral/alkaline ceramidase； N-酰基鞘氨醇酰胺水解酶2(ASAH2)； 酰基鞘氨醇脱酰酶2；
背景信息：
Ceramidases (EC 3.5.1.23), such as ASAH2, catalyze hydrolysis of the N-acyl linkage of ceramide, a second messenger in a variety of cellular events, to produce sphingosine. Sphingosine exerts both mitogenic and apoptosis-inducing activities, and its phosphorylated form functions as an intra- and intercellular second messenger (see MIM 603730) (Mitsutake et al., 2001 [PubMed 11328816]).[supplied by OMIM, Mar 2008]
