靶标:
Txndc17
产品别名:
4831443O22Rik; D11Ertd672e; TRP14; Txnl5; Txndc17; thioredoxin domain containing 17; thioredoxin domain containing 17; thioredoxin domain-containing protein 17; 14 kDa thioredoxin-related protein; protein 42-9-9; putative 42-9-9 protein; thioredoxin-like 5; thioredoxin-like protein 5;
背景信息:
function:Disulfide reductase. May participate in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyze dithiol-disulfide exchange reactions. Modulates TNF-alpha signaling and NF-kappa-B activation. Has peroxidase activity and may contribute to the elimination of cellular hydrogen peroxide.,PTM:The oxidized protein is reduced by TRXR1.,similarity:Belongs to the thioredoxin family.,similarity:Contains 1 thioredoxin domain.,subunit:Interacts with TRXR1 and DYNLL1/DNCL1.,tissue specificity:Ubiquitously expressed in cell lines.,