靶标：
ASB2
产品别名：
ASB-2； ASB2； ankyrin repeat and SOCS box containing 2； ankyrin repeat and SOCS box containing 2； ankyrin repeat and SOCS box protein 2； ankyrin repeat and SOCS box-containing protein 2a； 含锚蛋白重复序列-细胞因子信号抑制物盒蛋白家族2；
背景信息：
This gene encodes a member of the ankyrin repeat and SOCS box-containing (ASB) protein family. These proteins play a role in protein degradation by coupling suppressor of cytokine signalling (SOCS) proteins with the elongin BC complex. The encoded protein is a subunit of a multimeric E3 ubiquitin ligase complex that mediates the degradation of actin-binding proteins. This gene plays a role in retinoic acid-induced growth inhibition and differentiation of myeloid leukemia cells. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
