靶标：
CHMP5
产品别名：
C9orf83； CGI-34； HSPC177； PNAS-2； SNF7DC2； Vps60； CHMP5； charged multivesicular body protein 5； charged multivesicular body protein 5； charged multivesicular body protein 5； SNF7 domain containing 2； SNF7 domain-containing protein 2； apoptosis-related protein PNAS-2； chromatin-modifying protein 5； hVps60； vacuolar protein sorting-associated protein 60； 染色质修饰蛋白CHMP5；
背景信息：
CHMP5 belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).
