靶标:
INSIG2
产品别名:
INSIG-2; INSIG2; insulin induced gene 2; insulin induced gene 2; insulin-induced gene 2 protein; INSIG2 membrane protein; insulin induced protein 2; 胰岛素诱导基因2;
背景信息:
The protein encoded by this gene is highly similar to the protein product encoded by gene INSIG1. Both INSIG1 protein and this protein are endoplasmic reticulum proteins that block the processing of sterol regulatory element binding proteins (SREBPs) by binding to SREBP cleavage-activating protein (SCAP), and thus prevent SCAP from escorting SREBPs to the Golgi. [provided by RefSeq, Jul 2008],