靶标:
Myl12b
产品别名:
Mrlc2; Mrlcb; Mylc2b; Myl12b; myosin light chain 12B; myosin light chain 12B; myosin regulatory light chain 12B; MLC-2; MLC20; myosin RLC-B; myosin light chain, regulatory B; myosin regulatory light chain 20 kDa; myosin regulatory light chain MRLC2; myosin regulatory light chain-B; myosin, light chain 12B, regulatory; 肌球蛋白调节轻链12B; 肌球蛋白轻链12B(MYL12B);
背景信息:
This gene encodes a nonsarcomeric myosin regulatory light chain. This protein is activated by phosphorylation and regulates smooth muscle and non-muscle cell contraction. This protein may also be involved in DNA damage repair by sequestering the transcriptional regulator apoptosis-antagonizing transcription factor (AATF)/Che-1 which functions as a repressor of p53-driven apoptosis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 8.[provided by RefSeq, Dec 2014],