靶标：
DUOX2
产品别名：
LNOX2； NOXEF2； P138-TOX； TDH6； THOX2； DUOX2； dual oxidase 2； dual oxidase 2； dual oxidase 2； NADH/NADPH thyroid oxidase p138-tox； NADPH oxidase/peroxidase DUOX2； NADPH thyroid oxidase 2； dual oxidase-like domains 2； flavoprotein NADPH oxidase； large NOX 2； long NOX 2； nicotinamide adenine dinucleotide phosphate oxidase； p138 thyroid oxidase； thyroid oxidase 2； 双氧化酶2(DUOX2)； 双氧化酶2/甲状腺氧化酶2；
背景信息：
Dual oxidase 2, also known as DUOX2 or ThOX2 (for thyroid oxidase), is an enzyme that in humans is encoded by the DUOX2 gene. The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes this encoded protein and DUOX1. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain.
