靶标：
NENF
产品别名：
CIR2； SCIRP10； SPUF； NENF； neudesin neurotrophic factor； neudesin neurotrophic factor； neudesin； SCIRP10-related protein； Spinal cord injury related protein 10； cell growth-inhibiting protein 47； cell immortalization-related protein 2； neuron-derived neurotrophic factor； secreted protein of unknown function； Neudesin神经营养因子(NENF)； 神经元衍生神经营养因子(NDNF)； 神经源性神经营养因子；
背景信息：
NENF is a secreted protein that is expressed in neurons but not glial cells of the brain. This protein has neurotrophic activity in primary cultured mouse neurons but not mitogenic activity in primary cultured mouse astrocytes. NENF activated mitogen-activated protein (MAP) and phosphotidylinositol-3 kinase pathways and could be inhibited by pertussis toxin but not receptor tyrosine kinases, suggesting that NENF acts through a Gi/Go-protein-coupled receptor.
