靶标:
Ing4
产品别名:
D6Wsu147e; D6Xrf92; p29ING4; Ing4; inhibitor of growth family, member 4; inhibitor of growth family, member 4; inhibitor of growth protein 4; ING1-like protein;
背景信息:
This gene encodes a tumor suppressor protein that contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This protein can bind TP53 and EP300/p300, a component of the histone acetyl transferase complex, suggesting its involvement in the TP53-dependent regulatory pathway. Multiple alternatively spliced transcript variants have been observed that encode distinct proteins. [provided by RefSeq, Jul 2008],