靶标:
PDE7B
产品别名:
bA472E5.1; PDE7B; phosphodiesterase 7B; phosphodiesterase 7B; cAMP-specific 3',5'-cyclic phosphodiesterase 7B; high-affinity cAMP-specific 3',5'-cyclic phosphodiesterase; rolipram-insensitive phosphodiesterase type 7; 磷酸二酯酶7B;
背景信息:
The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a cAMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family.