靶标：
DNAI1
产品别名：
CILD1； DIC1； ICS1； PCD； DNAI1； dynein axonemal intermediate chain 1； dynein axonemal intermediate chain 1； dynein axonemal intermediate chain 1； dynein, axonemal, intermediate polypeptide 1； immotile cilia syndrome 1； testis tissue sperm-binding protein Li 87P； 胞浆动力蛋白中间链1； 轴丝中链动力蛋白；
背景信息：
This gene encodes a member of the dynein intermediate chain family. The encoded protein is part of the dynein complex in respiratory cilia. The inner- and outer-arm dyneins, which bridge between the doublet microtubules in axonemes, are the force-generating proteins responsible for the sliding movement in axonemes. The intermediate and light chains, thought to form the base of the dynein arm, help mediate attachment and may also participate in regulating dynein activity. Mutations in this gene result in abnormal ciliary ultrastructure and function associated with primary ciliary dyskinesia and Kartagener syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],
