靶标:
Racgap1
产品别名:
AI227039; AI327394; Band25; GTPase; MgcRacGAP; gtl11; mKIAA1478; Racgap1; Rac GTPase-activating protein 1; Rac GTPase-activating protein 1; rac GTPase-activating protein 1; male germ cell RacGap; Rac-GTP酶激活蛋白1(RACGAP1); Rho GTP酶激活蛋白GAP;
背景信息:
This gene encodes a GTPase-activating protein (GAP) that is a compoment of the centralspindlin complex. This protein binds activated forms of Rho GTPases and stimulates GTP hydrolysis, which results in negative regulation of Rho-mediated signals. This protein plays a regulatory role in cytokinesis, cell growth, and differentiation. Alternatively spliced transcript variants have been found for this gene. There is a pseudogene for this gene on chromosome 12. [provided by RefSeq, Feb 2016],