靶标:
DECR2
产品别名:
PDCR; SDR17C1; DECR2; 2,4-dienoyl-CoA reductase 2; 2,4-dienoyl-CoA reductase 2; peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]; 2,4-dienoyl-CoA reductase 2, peroxisomal; peroxisomal 2,4-dienoyl-CoA reductase; short chain dehydrogenase/reductase family 17C member 1; 过氧化物酶体2;
背景信息:
catalytic activity:Trans-2,3-didehydroacyl-CoA + NADP(+) = trans,trans-2,3,4,5-tetradehydroacyl-CoA + NADPH.,function:Auxiliary enzyme of beta-oxidation. Participates in the degradation of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions in peroxisome. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA. Has activity towards short and medium chain 2,4-dienoyl-CoAs, but also towards 2,4,7,10,13,16,19-docosaheptaenoyl-CoA, suggesting that it does not constitute a rate limiting step in the peroxisomal degradation of docosahexaenoic acid.,similarity:Belongs to the short-chain dehydrogenases/reductases (SDR) family.,similarity:Belongs to the short-chain dehydrogenases/reductases (SDR) family. 2,4-dienoyl-CoA reductase subfamily.,