靶标:
HACL1
产品别名:
2-HPCL; HPCL; HPCL2; PHYH2; HACL1; 2-hydroxyacyl-CoA lyase 1; 2-hydroxyacyl-CoA lyase 1; 2-hydroxyacyl-CoA lyase 1; 1600020H07Rik; 2-hydroxyphytanol-CoA lyase; 2-hydroxyphytanoyl-CoA lyase; phytanoyl-CoA 2-hydroxylase 2; phytanoyl-CoA hydroxylase 2; 植烷酰辅酶A羟化酶2;
背景信息:
HACL1 (2-hydroxyacyl-CoA lyase 1) is also known as HPCL or 2-HPCL (2-hydroxyphytanoyl-CoA lyase) and is a 578 amino acid protein. HACL1 is abundantly expressed in liver, and is also expressed in kidney, heart and skeletal muscle, where it is localized to peroxisomes. HACL1 functions in lipid metabolism as well as fatty acid metabolism and is able to form homotetramers.