靶标:
ACOT11
产品别名:
BFIT; STARD14; THEA; THEM1; ACOT11; acyl-CoA thioesterase 11; acyl-CoA thioesterase 11; acyl-coenzyme A thioesterase 11; START domain containing 14; StAR-related lipid transfer (START) domain containing 14; acyl-CoA thioester hydrolase 11; adipose-associated thioesterase; brown fat-inducible thioesterase; palmitoyl-coenzyme A thioesterase; thioesterase superfamily member 1; thioesterase, adipose associated;
背景信息:
This gene encodes a member of the acyl-CoA thioesterase family which catalyse the conversion of activated fatty acids to the corresponding non-esterified fatty acid and coenzyme A. Expression of a mouse homolog in brown adipose tissue is induced by low temperatures and repressed by warm temperatures. Higher levels of expression of the mouse homolog has been found in obesity-resistant mice compared with obesity-prone mice, suggesting a role of acyl-CoA thioesterase 11 in obesity. Alternative splicing results in transcript variants. [provided by RefSeq, Nov 2010],