靶标:
NECTIN3
产品别名:
CD113; CDW113; NECTIN-3; PPR3; PRR3; PVRL3; PVRR3; NECTIN3; nectin cell adhesion molecule 3; nectin cell adhesion molecule 3; nectin-3; nectin 3; poliovirus receptor-related 3; poliovirus receptor-related protein 3; 脊髓灰质炎病毒受体相关分子3(PVRL3); 连接蛋白3;
背景信息:
This gene encodes a member of the nectin family of proteins, which function as adhesion molecules at adherens junctions. This family member interacts with other nectin-like proteins and with afadin, a filamentous actin-binding protein involved in the regulation of directional motility, cell proliferation and survival. This gene plays a role in ocular development involving the ciliary body. Mutations in this gene are believed to result in congenital ocular defects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011],