靶标：
RNF19A
产品别名：
RNF19； RNF19A； ring finger protein 19A, RBR E3 ubiquitin protein ligase； ring finger protein 19A, RBR E3 ubiquitin protein ligase； E3 ubiquitin-protein ligase RNF19A； double ring-finger protein； protein p38 interacting with transcription factor Sp1； ring finger protein 19A, E3 ubiquitin protein ligase； ring-IBR-ring domain containing protein Dorfin； 环指蛋白19；
背景信息：
This gene encodes a member of the ring between ring fingers (RBR) protein family, and the encoded protein contains two RING-finger motifs and an in between RING fingers motif. This protein is an E3 ubiquitin ligase that is localized to Lewy bodies, and ubiquitylates synphilin-1, which is an interacting protein of alpha synuclein in neurons. The encoded protein may be involved in amyotrophic lateral sclerosis and Parkinson's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],
