靶标：
Grem2
产品别名：
Gremlin2； Prdc； Grem2； gremlin 2, DAN family BMP antagonist； gremlin 2, DAN family BMP antagonist； gremlin-2； Gremlin1； cysteine knot superfamily 1, BMP antagonist 2； gremlin 2 homolog, cysteine knot superfamily； protein related to DAN and cerberus； Gremlin 2蛋白(GREM2)； 骨形态形成蛋白拮抗蛋白2；
背景信息：
This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. [provided by RefSeq, Jul 2008],
