靶标:
MKRN2
产品别名:
HSPC070; RNF62; MKRN2; makorin ring finger protein 2; makorin ring finger protein 2; E3 ubiquitin-protein ligase makorin-2; RING finger protein 62; RING-type E3 ubiquitin transferase makorin-2; makorin RING zinc-finger protein 2; probable E3 ubiquitin-protein ligase makorin-2; 环指蛋白62;
背景信息:
MKRN2 gene encodes a probable E3 ubiquitin ligase containing several zinc finger domains, that is a member of the makorin RING zinc-finger protein family. This gene overlaps the v-raf-1 murine leukemia viral oncogene homolog 1 (RAF1) gene in an antisense orientation and may have a co-regulatory function with RAF1. Alternative splicing results in multiple transcript variants. E3 ubiquitin ligase catalyze the covalent attachment of ubiquitin moieties onto substrate proteins.