靶标：
QPRT
产品别名：
HEL-S-90n； QPRTase； QPRT； quinolinate phosphoribosyltransferase； quinolinate phosphoribosyltransferase； nicotinate-nucleotide pyrophosphorylase [carboxylating]； epididymis secretory sperm binding protein Li 90n； nicotinate-nucleotide pyrophosphorylase (carboxylating)； 喹啉酸磷酸核糖基转移酶；
背景信息：
This gene encodes a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease, and Huntington's disease. Alternative splicing results in multiple transcript variants.
