靶标：
TRAM1
产品别名：
PNAS8； TRAM； TRAMP； TRAM1； translocation associated membrane protein 1； translocation associated membrane protein 1； translocating chain-associated membrane protein 1； translocating chain-associating membrane protein； translocation-associating membrane protein 1； 易位关联膜蛋白1(TRAM1)； 相关易位膜蛋白1；
背景信息：
TRAM1(Translocation-Associating Membrane Protein 1), By crosslinking and reconstitution of canine proteoliposomes, followed by microsequencing and PCR screening of canine kidney and HeLa cell cDNA libraries, Gorlich et al.(1992) isolated cDNAs encoding TRAM(translocating chain-associating membrane protein). The International Radiation Hybrid Mapping Consortium mapped the TRAM gene to chromosome 8. Sequence analysis predicted that human TRAM is a 374-amino acid, 8-pass transmembrane protein that shares 95% amino acid identity with the canine protein. Functional analysis indicated that TRAM influences glycosylation and is stimulatory or required for the translocation of secretory proteins.
