靶标：
GCAT
产品别名：
KBL； GCAT； glycine C-acetyltransferase； glycine C-acetyltransferase； 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial； 2-amino-3-ketobutyrate-CoA ligase； AKB ligase； aminoacetone synthase； glycine acetyltransferase； 氨基丙酮合成酶；
背景信息：
The degradation of L-threonine to glycine consists of a two-step biochemical pathway involving the enzymes L-threonine dehydrogenase and 2-amino-3-ketobutyrate coenzyme A ligase. L-Threonine is first converted into 2-amino-3-ketobutyrate by L-threonine dehydrogenase. This gene encodes the second enzyme in this pathway, which then catalyzes the reaction between 2-amino-3-ketobutyrate and coenzyme A to form glycine and acetyl-CoA. The encoded enzyme is considered a class II pyridoxal-phosphate-dependent aminotransferase. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 14.
