靶标:
ICMT
产品别名:
HSTE14; MST098; MSTP098; PCCMT; PCMT; PPMT; ICMT; isoprenylcysteine carboxyl methyltransferase; isoprenylcysteine carboxyl methyltransferase; protein-S-isoprenylcysteine O-methyltransferase; prenylated protein carboxyl methyltransferase; prenylcysteine carboxyl methyltransferase; 异戊烯半胱氨酸羧基甲基转移酶;
背景信息:
This gene encodes the third of three enzymes that posttranslationally modify isoprenylated C-terminal cysteine residues in certain proteins and target those proteins to the cell membrane. This enzyme localizes to the endoplasmic reticulum. Alternative splicing may result in other transcript variants, but the biological validity of those transcripts has not been determined.