靶标：
TRIM2
产品别名：
CMT2R； RNF86； TRIM2； tripartite motif containing 2； tripartite motif containing 2； tripartite motif-containing protein 2； Charcot-Marie-Tooth disease, type 2R； E3 ubiquitin-protein ligase TRIM2； RING finger protein 86； RING-type E3 ubiquitin transferase TRIM2； tripartite motif protein TRIM2； 环指蛋白86；
背景信息：
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic filaments. It plays a neuroprotective role and functions as an E3-ubiquitin ligase in proteasome-mediated degradation of target proteins. Mutations in this gene can cause early-onset axonal neuropathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014],
