靶标：
ANKRD28
产品别名：
CFAP79； FAP79； PITK； PPP1R65； ANKRD28； ankyrin repeat domain 28； ankyrin repeat domain 28； serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A； PP6-ARS-A； ankyrin repeat domain-containing protein 28； phosphatase interactor targeting K protein； phosphatase interactor targeting protein hnRNP K； protein phosphatase 1, regulatory subunit 65； protein phosphatase 6 ankyrin repeat subunit A； serine/threonine-protein phosphatase 6 regulatory subunit ARS-A； 锚蛋白重复域28；
背景信息：
function:Putative regulatory subunit of protein phospatase 6 (PP6) that may be involved in the recognition of phosphoprotein substrates. Involved in the PP6-mediated dephosphorylation of NFKBIE opposing its degradation in response to TNF-alpha. Selectively inhibits the phosphatase activity of PPP1C. Targets PPP1C to modulate HNRPK phosphorylation.,similarity:Contains 27 ANK repeats.,subcellular location:Seems to be excluded from nucleoli.,subunit:Protein phospatase 6 (PP6) holoenzyme is proposed to be a heterotrimeric complex formed by the catalytic subunit, a SAPS domain-containing subunit (PP6R) and an ankyrin repeat-domain containing regulatory subunit (ARS). Interacts with PPP1C and HNRPK. Interacts with PPP6C, SAPS1 and SAPS3.,
