靶标:
ATF5
产品别名:
ATFX; HMFN0395; ATF5; activating transcription factor 5; activating transcription factor 5; cyclic AMP-dependent transcription factor ATF-5; cAMP-dependent transcription factor ATF-5; transcription factor ATFx; 活化转录因子5;
背景信息:
function:Transcriptional activator which binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters and blocks the differentiation of neuroprogenitor cells into neurons. Its transcriptional activity is enhanced by CCND3 and slightly inhibited by CDK4.,similarity:Belongs to the bZIP family.,similarity:Contains 1 bZIP domain.,subunit:Binds DNA as a dimer. Interacts with PTP4A1/PRL-1 (By similarity). Interacts with CCND3, but not with CCND1 or CCND2.,