靶标:
Sftpa1
产品别名:
SP-A; Sftp-1; Sftp1; Sftpa1; surfactant associated protein A1; surfactant associated protein A1; pulmonary surfactant-associated protein A; PSAP; PSP-A; surfactant pulmonary associated protein A1; 肺表面活性蛋白A; 表面活性物质关联蛋白A(SFTPA1);
背景信息:
This gene encodes a lung surfactant protein that is a member of a subfamily of C-type lectins called collectins. The encoded protein binds specific carbohydrate moieties found on lipids and on the surface of microorganisms. This protein plays an essential role in surfactant homeostasis and in the defense against respiratory pathogens. Mutations in this gene are associated with idiopathic pulmonary fibrosis. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010],