靶标：
Ntsr2
产品别名：
NT-R-2； NT2R； NTR2； NTRL； Ntsr2； neurotensin receptor 2； neurotensin receptor 2； neurotensin receptor type 2； low affinity neurotensin receptor； low-affinity levocabastine-sensitive neurotensin receptor； 神经降压素受体2； 神经降压素受体2(NTSR2)；
背景信息：
The protein encoded by this gene belongs to the G protein-coupled receptor family that activate a phosphatidylinositol-calcium second messenger system. Binding and pharmacological studies demonstrate that this receptor binds neurotensin as well as several other ligands already described for neurotensin NT1 receptor. However, unlike NT1 receptor, this gene recognizes, with high affinity, levocabastine, a histamine H1 receptor antagonist previously shown to compete with neurotensin for low-affinity binding sites in brain. These activities suggest that this receptor may be of physiological importance and that a natural agonist for the receptor may exist. [provided by RefSeq, Jul 2008],
