靶标:
Mxd3
产品别名:
4631412E13Rik; Mad3; bHLHc13; Mxd3; Max dimerization protein 3; Max dimerization protein 3; max dimerization protein 3; max dimerizer 3; max-associated protein 3; MAD3蛋白;
背景信息:
This gene encodes a member of the Myc superfamily of basic helix-loop-helix leucine zipper transcriptional regulators. The encoded protein forms a heterodimer with the cofactor MAX which binds specific E-box DNA motifs in the promoters of target genes and regulates their transcription. Disruption of the MAX-MXD3 complex is associated with uncontrolled cell proliferation and tumorigenesis. Transcript variants of this gene encoding different isoforms have been described.[provided by RefSeq, Dec 2008]