靶标:
Hao1
产品别名:
GOX; Gox1; Hao-1; Hao1; hydroxyacid oxidase 1, liver; hydroxyacid oxidase 1, liver; 2-Hydroxyacid oxidase 1; HAOX1; glycolate oxidase 1; glyoxylate oxidase; 羟酸氧化酶1(HAO1); 葡萄糖氧化酶1;
背景信息:
This gene is one of three related genes that have 2-hydroxyacid oxidase activity yet differ in encoded protein amino acid sequence, tissue expression and substrate preference. Subcellular location of the encoded protein is the peroxisome. Specifically, this gene is expressed primarily in liver and pancreas and the encoded protein is most active on glycolate, a two-carbon substrate. The protein is also active on 2-hydroxy fatty acids. The transcript detected at high levels in pancreas may represent an alternatively spliced form or the use of a multiple near-consensus upstream polyadenylation site. [provided by RefSeq, Jul 2008],