靶标:
Ganab
产品别名:
AU042638; G2an; GluII; mKIAA0088; Ganab; alpha glucosidase 2 alpha neutral subunit; alpha glucosidase 2 alpha neutral subunit; neutral alpha-glucosidase AB; alpha-glucosidase 2; carbohydrate processing enzyme of the endoplasmic reticulum; glucosidase II alpha-subunit; glucosidase II subunit alpha; α葡萄糖苷酶2; 中性葡糖苷酶αAB(GaNAB);
背景信息:
This gene encodes the alpha subunit of glucosidase II and a member of the glycosyl hydrolase 31 family of proteins. The heterodimeric enzyme glucosidase II plays a role in protein folding and quality control by cleaving glucose residues from immature glycoproteins in the endoplasmic reticulum. Expression of the encoded protein is elevated in lung tumor tissue and in response to UV irradiation. Mutations in this gene cause autosomal-dominant polycystic kidney and liver disease. [provided by RefSeq, Jul 2016],