靶标:
Bop1
产品别名:
AU020183; AW146150; D18861; Erb1p; Kiaa0124; mKIAA0124; Bop1; block of proliferation 1; block of proliferation 1; ribosome biogenesis protein BOP1; block of proliferation 1 protein; 核糖体合成蛋白BOP1;
背景信息:
function:Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.,induction:By MYC.,similarity:Belongs to the WD repeat BOP1/ERB1 family.,similarity:Contains 7 WD repeats.,subunit:Component of the PeBoW complex, composed of bop1, pes1 and wdr12. Within the PeBoW complex bop1 interacts directly with pes1 and wdr12. The PeBoW complex also associates with the 66S pre-ribosome.,