靶标:
SNF8
产品别名:
Dot3; EAP30; VPS22; SNF8; SNF8 subunit of ESCRT-II; SNF8 subunit of ESCRT-II; vacuolar-sorting protein SNF8; EAP30 subunit of ELL complex; ELL-associated protein of 30 kDa; ESCRT-II complex subunit VPS22; SNF8, ESCRT-II complex subunit, homolog; EAP30蛋白;
背景信息:
The protein encoded by this gene is a component of the endosomal sorting complex required for transport II (ESCRT-II), which regulates the movement of ubiquitinylated transmembrane proteins to the lysosome for degradation. This complex also interacts with the RNA polymerase II elongation factor (ELL) to overcome the repressive effects of ELL on RNA polymerase II activity. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015],