靶标:
IL1RAPL1
产品别名:
IL-1-RAPL-1; IL-1RAPL-1; IL1R8; IL1RAPL; IL1RAPL-1; MRX10; MRX21; MRX34; OPHN4; TIGIRR-2; IL1RAPL1; interleukin 1 receptor accessory protein like 1; interleukin 1 receptor accessory protein like 1; interleukin-1 receptor accessory protein-like 1; X-linked interleukin-1 receptor accessory protein-like 1; interleukin 1 receptor-8; oligophrenin-4; three immunoglobulin domain-containing IL-1 receptor-related 2; 白介素1受体相关蛋白样1前体蛋白; 白介素1受体辅助蛋白样蛋白1(IL1RAPL1);
背景信息:
The protein encoded by this gene is a member of the interleukin 1 receptor family and is similar to the interleukin 1 accessory proteins. It is most closely related to interleukin 1 receptor accessory protein-like 2 (IL1RAPL2). This gene and IL1RAPL2 are located at a region on chromosome X that is associated with X-linked non-syndromic mental retardation. Deletions and mutations in this gene were found in patients with mental retardation. This gene is expressed at a high level in post-natal brain structures involved in the hippocampal memory system, which suggests a specialized role in the physiological processes underlying memory and learning abilities. [provided by RefSeq, Jul 2008],