靶标:
BTN2A1
产品别名:
BK14H9.1; BT2.1; BTF1; BTN2.1; DJ3E1.1; BTN2A1; butyrophilin subfamily 2 member A1; butyrophilin subfamily 2 member A1; 嗜乳脂蛋白2亚型A1;
背景信息:
This gene encodes a member of the immunoglobulin superfamily. The gene is located in a cluster of butyrophilin-like genes in the juxta-telomeric region of the major histocompatibility complex on chromosome 6. A pseudogene of this gene has been identified in this cluster. The encoded protein is an integral plasma membrane protein involved in lipid, fatty-acid, and sterol metabolism. Alterations in this gene may be associated with several disease states including metabolic syndrome. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.